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Ulcerative colitis is a form of inflammatory bowel disease affecting the large intestine (sometimes called the large bowel or colon) and rectum. Ulcerative colitis is a rare disease, with an incidence of about one person per 10,000 in North America. Ulcerative colitis is generally curable by total colectomy, while Crohn’s colitis is likely to recur in the small bowel after the colon is removed. In the best cases, ulcerative colitis relief may lead not only to symptom relief but also to long-term remission. Ulcerative colitis treatment usually involves either drug therapy or surgery. Doctors use several categories of drugs that control inflammation in different ways.